Puppy Vaccine Schedule For First-Year Shots [PDF Chart]

Rabies Vaccine

Rabies is a viral infection caused by a virus secreted in the saliva. According to the Humane Society, because the infection affects the nervous system, most rabid animals behave abnormally. Infected dogs typically become fearful, anxious, agitated, and/or aggressive. As there’s no cure for rabies, keeping up with regular vaccinations is crucial.

When should puppies get rabies shots?

Generally speaking, puppies should get their first rabies shot around 16 weeks of age and again between 1-3 years old. The rabies vaccine is mandatory throughout the US, but the timeline for a puppy schedule varies by state**. The vaccine must be administered by a licensed veterinarian (which means it can’t be found at a feed store).

Rabies Vaccine Schedule for Puppies

• 1st shot: 16-18 weeks
• 2nd shot: 1 year
• Booster: every 3 years

Non-core Vaccines

Non-core vaccines are important, but they are considered optional for dogs with less risk of infection. Non-core vaccines are recommended based on lifestyle and where you live or travel.

Bordetella

Bordetella bronchiseptica is a bacterium associated with respiratory disease in dogs and is known to cause the most severe form of kennel cough. Symptoms of an upper respiratory infection include nasal discharge, sneezing, coughing, congestion, etc.

Some veterinarians may recommend Bordetella as a core vaccine for puppies based on their living environment, especially for social dogs who spend time in areas where they might come into contact with the bacteria (like the dog park, boarding facilities, or doggy daycare). The vaccination can be given orally, intranasally, or by injection.

Bordetella Vaccine Schedule for Puppies

• 1st shot: 12-14 weeks
• 2nd shot: 1 year
• Booster: every year

Leptospira

Leptospirosis is a bacterial disease caused by infection of the genus Leptospira, which are found in water and soil. The zoonotic disease spreads easily from animals to humans and is more common in warm climate areas with high annual rainfall; the Leptospira vaccine may be considered core in these areas.

Signs of leptospirosis may include shivering, fever, muscle tenderness, increased thirst, dehydration, diarrhea, vomiting, lethargy, jaundice, kidney failure, liver failure, etc. When the disease is treated early and aggressively, the chances for recovery are quite good but there’s still a risk of permanent kidney/liver damage.

Leptospira Vaccine Schedule for Puppies

• 1st shot: 12-14 weeks
• 2nd shot: 16-18 weeks
• 3rd shot: 1 year
• Booster: every year

There is also a 5-way vaccine known as DHLPP, which is a combination vaccine of distemper, hepatitis, leptospirosis, parainfluenza, and parvo.

Lyme disease

Lyme disease is caused by infection with the bacterium Borrelia burgdorferi which is transmitted through the bite of infected ticks. The most common symptoms in dogs include loss of appetite, lameness, joint swelling, swollen lymph nodes, and fatigue. More serious cases can also develop kidney complications.

The Lyme disease vaccine is highly recommended for dogs that live in or frequently travel to areas known for Lyme disease, as well as those living in areas with a high risk of tick exposure.

Lyme Vaccination Schedule for Puppies

• 1st shot: 10-16 weeks
• 2nd shot: 2-3 weeks later
• Booster: every year

Canine Influenza

Canine influenza, or dog flu, is a contagious viral infection affecting dogs. Two strains of canine influenza virus (CIV) have been identified in the US: H3N2 and H3N8.

The virus is spread through aerosols or droplets containing respiratory secretions from barking, sneezing, and coughing. Dogs in close contact with infected dogs in places like daycare facilities, groomers, and kennels are at a higher risk of contracting the disease. CIV causes an acute respiratory infection in dogs, with the most common clinical sign being a cough that persists for up to 21 days.

Vaccines are available for both H3N2 and H3N8 canine influenza. A bivalent vaccine offering protection against both strains is available as well.

Canine Influenza Vaccine Schedule For Puppies

• 1st shot: <16 weeks
• 2nd shot: 2-4 weeks later

Giardia

Giardia is a parasite that lives in dogs’ intestines and most often infects puppies and older dogs. Dogs become infected when they swallow the parasite that may be present in water or other substances that have been soiled with feces leading to the disease Giardiasis. Giardia in dogs usually causes diarrhea, weight loss, or even death.

Giardia is an available vaccine for puppies 8 weeks of age and older for 6 months of immunity against giardiasis.

Coronavirus

The canine coronavirus is not in any way similar to COVID-19 in people. Canine coronavirus usually affects a dog’s GI system, but it can also cause respiratory infections. Most common symptoms include vomiting, diarrhea, and loss of appetite.

Young dogs are at a high risk of contracting the disease, so the vaccine is highly recommended for puppies under eight weeks. It’s usually not continued in puppies over eight weeks, but may be based on your vet’s recommendation.

Rattlesnake vaccine

A rattlesnake vaccine can help dogs build antibodies to rattlesnake venom from bites that are often deadly and severely painful to dogs. The antibodies work to neutralize the venom, thereby significantly extending the window of time you have to take your dog to the emergency room, increasing their odds of survival.