Pet Care Blog

Osteosarcoma (Bone Cancer) in Dogs: Causes, Symptoms, Treatment

Dr. Ricky Walther
Veterinarian
Large dog laying on vet table licking owner's hand

Osteosarcoma is a diagnosis that no pet parent wants to hear. The symptoms can be subtle, which is why owners need to know how to recognize them and seek treatment as soon as possible. The good news is, although the prognosis can be rather discouraging, there are options that could extend your pet’s life.

Table of Contents:

Pro Tip: In some cases, pet parents might not be able to afford the costs of chemotherapy and surgery. Pet insurance can help you avoid this situation. Compare pet insurance plans now to find the one that best suits your pup’s needs.

What is osteosarcoma?

Osteosarcoma (OS or OSA) is a malignant bone tumor comprised of naturally occurring cancer cells that can quickly and aggressively spread to other parts of the body. In most cases, canine osteosarcoma develops as a large, hard lump on the dogs’ front legs. However, the dog’s rear legs, facial bones, jaw, vertebrae, ribs, and hips may also be affected.

The tumor, or sarcoma, can be rather painful, often causing dogs to walk with a limp to avoid placing pressure on the affected limb. If cancer metastasizes (spreads throughout the body), it can lead to many secondary health issues, such as respiratory distress upon impairment of the lungs.

How common is osteosarcoma?

OSA is the most common subtype of primary bone tumor in dogs and humans, making up more than 95% of all cases of canine bone cancer. Other types of bone cancer include fibrosarcoma, chondrosarcoma, and hemangiosarcoma. (Note that “primary” indicates where the disease originated, rather than metastatic cancer in the legs, ribs, or hips seeping into the bone that started somewhere else.)

Bone cancer is a rare disease in humans, but studies reveal incidence rates are 27 times higher in dogs.

Is osteosarcoma hereditary in dogs?

Several genetic risk factors increase the likelihood of a dog developing osteosarcoma. Male dogs also tend to suffer from bone cancer more often than females, as do dogs who are neutered or spayed before they turn one. The disease appears to be more prevalent among young dogs between 18 and 24 months old, in addition to seniors aged seven to nine.

Golden Retriever dog with osteosarcoma bone cancer

What dog breeds are prone to cancer?

There also appears to be a genetic risk factor present in large- and giant-sized dogs, with a higher prevalence of bone cancer in breeds such as:

Note that there are several types of cancer in dogs, and breeds prone to bone cancer are not necessarily genetically predisposed to lymphoma, for example.

What causes osteosarcoma in dogs?

The causes of osteosarcoma in dogs are unclear. Some theories suggest the disease development might be related to prior fractures, underlying bone diseases, and repeated bone injuries.

In most cases, multiple factors contribute to cancer in canines, some of which are hereditary while others are environmental. Osteosarcoma can affect all dogs, so it’s best to monitor your pet’s health with annual veterinary visits and be mindful of potential symptoms of bone cancer.

What are the symptoms of osteosarcoma?

The signs of a bone tumor in dogs can be subtle, making it challenging to detect early-stage osteosarcoma. Cancer first develops deep within the bone, so your pup might not feel any initial pain or discomfort. As cancer progresses and the tumor grows, you may notice them displaying the symptoms of osteosarcoma in dogs, including:

  • Constant or intermittent inability to use one or more limbs (lameness)
  • Lethargy
  • Loss of appetite
  • Joint pain
  • Swelling or a mass, especially if the tumor is in the ribs, jaw, or skull
  • Neurologic symptoms, like wobbly gait or seizures, if the bone cancer is in the spine or skull
  • Difficulty opening the mouth, chewing, or eating if the tumor affects the jaw
  • Breathing difficulties due to rib tumors
  • As it grows, the cancer will weaken the bone, which can cause a break or fracture

Be sure to see your veterinarian ASAP at first sight of a dog’s bone cancer symptoms. Canine osteosarcoma is extremely aggressive, and a swift diagnosis could help extend your pet’s life.

How to tell if a dog has cancer

Your vet will perform a general physical exam, as well as an orthopedic exam to rule out other potential causes of lameness.

The vet will also take X-rays, especially if there’s a lump on a dog’s leg. If they identify any problematic areas, a bone biopsy may be necessary to obtain a definitive diagnosis.

They might also order chest X-rays, a CT scan, and blood tests to assess the pet’s overall health and determine whether cancer has metastasized. Unfortunately, in more than 90% of dogs, the tumor will have already spread by the time of diagnosis, most commonly to the lungs.

If you suspect a bone tumor in your dog, be sure to talk to your vet immediately. They can make a proper diagnosis and discuss treatment options with you.

Close-up of amputee dog missing one leg wearing a bandana

How to treat cancer in dogs

Treatment for osteosarcoma in dogs will depend on several factors, including the location of the tumor and whether the cancer has spread.

If the tumor location is in the limb, a veterinarian** will likely recommend amputation due to the cancer’s aggressive nature. Although it may sound like a very drastic step, dogs can function very well with three legs. Amputation is typically followed by chemotherapy to help extend the animal’s life.

When the surgical procedure is not possible due to the tumor location, stereotactic radiation can be beneficial. This may be an option before amputation in early-stage osteosarcoma if the cancer hasn’t affected a significant portion of the bone.

Palliative care aims to make a dog’s final days or weeks more pleasant with the proper use of pain management drugs, dietary strategies, and human interaction. It can also include conventional radiation therapy for pain relief.

How much does canine chemotherapy cost?

Osteosarcoma treatment costs can be very high, extending well beyond the $10,000 mark. It’s hard to determine the average cost of cancer treatment for dogs due to several variables, such as the dog's size, affecting the amount of chemotherapy required. Here's a breakdown of veterinary costs you can expect for bone cancer treatment in dogs:

  • Cost of diagnostic testing with an oncologist - $800 to $1,000
  • Cost to remove the dog's tumor, depending on its location and the surgeon’s degree of specialization - $1,000 to $3,000
  • Cost of canine chemotherapy treatment - $2,000 to $4,000
  • Additional palliative radiation cost - $2,000 to $5,000

Pro Tip: If your dog is prone to cancer, consider enrolling in a pet insurance plan while they’re still in good health. Hopefully, your pup is free of osteosarcoma, but pet insurance can help with other types of cancers, like skin cancer, as well as common illnesses, such as kennel cough.

Prognosis, recovery, and life expectancy of dogs with cancer

The prognosis for osteosarcoma in dogs will depend on several factors, including the severity of the disease and the selected treatment method. If you detect early-stage osteosarcoma and start treatment before cancer spreads, the chances of survival are better.** **If osteosarcoma metastisizes and extends to the lymph nodes, lungs, or other parts of the body, the dog’s outlook will be very poor.

Dogs with bone cancer have a median life expectancy of about a year if they receive chemotherapy and stereotactic radiation. The osteosarcoma survival time is similar for pets treated with amputation followed by chemotherapy. In contrast, with amputation alone, dogs can live with cancer usually for about three months. About 15% to 30% of dogs can expect a survival time of two years.

Osteosarcoma is often fatal, even with therapy and surgery. For this reason, many pet parents decide not to pursue treatment and instead choose euthanasia as the kindest option.

If your dog has osteosarcoma, consult your vet to determine the most appropriate course of action for you and your family.

Key Takeaways

  • Osteosarcoma is a malignant bone tumor typically found in dogs’ limbs but can be located anywhere in the body.
  • Giant breeds are most at risk of developing canine osteosarcoma, but veterinarians aren’t entirely sure what causes bone cancer in dogs.
  • This type of bone cancer is very aggressive in dogs and can quickly metastasize to other parts of the body, most often the lungs.
  • Contact your vet at first sight of a lump on a dog’s leg. Knowing how to recognize canine osteosarcoma symptoms can help minimize the spread of cancerous cells and maximize your loved one’s quality of life.

Do you want to find the best pet insurance?

Let's analyze your pet's breed, age, and location to find the right coverage and the best savings. Ready?

Analyze My Pet

About Pawlicy Advisor

The pet insurance marketplace endorsed by veterinarians, at Pawlicy Advisor we make buying the best pet insurance easier. By comparing personalized coverage and pricing differences we can save you a ton of money, up to 83% in some instances!

Pawlicy Advisor helping a pet parent and their dog find a great deal on insurance

Instantly Compare Pet Insurance Plans

Get Quotes

Guides

How Pet Insurance Works

How To Compare Plans

Determine If Pet Insurance Is Worth It

Determine If Wellness Plans Are Worth It

Vet Visit Costs

New Puppy Checklist

Comparison Charts

ASPCA vs. Pets Best

Pets Best vs. Embrace

Embrace vs. Pumpkin

Pumpkin vs. MetLife

More Comparison Charts

Find Your State

New Jersey

California

Florida

Oregon

Texas

New York

Colorado

Pennsylvania

More States

Dog Insurance

German Shepherd

Rottweiler

Akita

Boxer

English Bulldog

French Bulldog

Great Dane

Pug

Corgi

Chihuahua

Poodle

More Breeds

Ricky Walther, DVM

Dr. Ricky Walther
Veterinarian

Ricky Walther, DVM, is a small animal general practitioner in the greater Sacramento, California area. Realizing the positive financial and medical impact that pet insurance can provide for pet parents and the profession, he lends support and advice to companies like Pawlicy Advisor "The Pet Insurance Marketplace") that simplify the process of connecting with veterinary financing resources.

More you might like

Dog wants to eat fruit dessert plate on table
12 minute read
List of Food Dogs Can (and Can't) Eat, According to Vet
Garlic peeled and diced on cutting board
6 minute read
Can Dogs Eat Garlic? Here's Everything You Need to Know
American Foxhound dog tilting head
6 minute read
Ataxia in Dogs: Causes, Symptoms, and Treatment
Dog with conjunctivitis eye problem
6 minute read
Conjunctivitis (Pink Eye) in Dogs: Causes, Symptoms, Treatment
White cat cleaning rear end with tongue
5 minute read
Tapeworms in Cats: Causes, Symptoms, Treatment
Brown Labrador Retriever puppy laying on grass
31 minute read
Labrador Retriever Growth & Weight Chart: Everything You Need To Know
Basset Hound puppy sitting outside in sun
7 minute read
Basset Hound Growth & Weight Chart: Everything You Need to Know
Havanese puppy with black and white spots
6 minute read
Havanese Growth & Weight Chart: Everything You Need to Know
Maltese puppy close-up
7 minute read
Maltese Growth & Weight Chart: Everything You Need To Know
Pomeranian puppy standing in grass
8 minute read
Pomeranian Growth & Weight Chart: Everything You Need to Know
Dachshund puppy at home in bedroom
5 minute read
Dachshund Growth & Weight Chart: Everything You Need To Know
Greyhound puppy running toward camera
5 minute read
Greyhound Growth & Weight Chart: Everything You Need to Know
Jack Russell Terrier puppy
6 minute read
Jack Russell Terrier Growth & Weight Chart: Everything You Need to Know
Newfoundland puppy with tongue sticking out
5 minute read
Newfoundland Growth & Weight Chart: Everything You Need to Know
Bernese Mountain Dog puppy laying in field
7 minute read
Bernese Mountain Dog Growth & Weight Chart: Everything You Need to Know
Siberian Husky puppy
7 minute read
Siberian Husky Growth & Weight Chart: Must-Know Health Facts
Dog and vet looking at medical chart
14 minute read
Dog Health Issues: Common Conditions by Breed, Size, Age
Dog receives eye drops for glaucoma treatment
6 minute read
Glaucoma in Dogs: Causes, Symptoms & Treatment
Dog looking up at owner begging for glass of milk
9 minute read
Can Dogs Drink Milk? Here's Everything You Need to Know
Dog holding coconut in mouth on beach
7 minute read
Can Dogs Eat Coconut? Here's Everything You Need to Know
Tuna sandwich with bite marks
6 minute read
Can Dogs Eat Tuna? Here's Everything You Need to Know

7 minute read
Labradoodle Growth & Weight Chart: Everything You Need to Know
St. Bernard puppy with mouth open
7 minute read
Saint Bernard Growth & Weight Chart: Everything You Need to Know
Pit Bull puppy lying in grass smiling
6 minute read
Pit Bull Growth & Weight Chart: Everything You Need to Know
Dog on newspaper looking ashamed
7 minute read
Colitis in Dogs: Symptoms, Diagnosis, Treatment
Glucosamine supplement for dog
7 minute read
Glucosamine For Dogs: Uses, Dosage & Side Effects
Hypothyroidism in overweight dog smiling sitting up
6 minute read
Hypothyroidism in Dogs: Causes, Symptoms, Treatments
Can Cats Eat Watermelon
5 minute read
Can Cats Eat Watermelon? Here's Everything You Need to Know
Can cats eat eggs
6 minute read
Can Cats Eat Eggs? Here's Everything You Need to Know
Close-up of avocado toast with spinach
11 minute read
Can Dogs Eat Spinach? Here's Everything You Need to Know
Mother and daughter preparing green beans with dog
11 minute read
Can Dogs Eat Green Beans? Here's Everything You Need to Know
Cat dislikes taste of food in mouth
6 minute read
Can Cats Eat Peanut Butter? Here's Everything You Need to Know
Dog looking at bowl of walnuts on table
5 minute read
Can Dogs Eat Walnuts? Here's Everything You Need to Know
Dog in birthday hat eating cinnamon cake
5 minute read
Can Dogs Eat Cinnamon? Here's Everything You Need to Know
Dog scratching ear with rear paw
6 minute read
Ear Mites in Dogs: Everything You Need to Know
Cat looking at pill capsules on the floor
5 minute read
Gabapentin for Cats: Uses, Dosage, Side Effects
Close-up of dog sleeping on the couch
7 minute read
Melatonin For Dogs: Uses, Dosage, & Side Effects
Dog lying on bed wrapped in blankets
6 minute read
Distemper in Dogs: Symptoms, Treatment, Prevention
Hand holding pill tablet above dog
7 minute read
Prednisone (Prednisolone) For Dogs: Uses, Dosage, Side Effects
Dog abdomen with bandage from surgery
8 minute read
Pyometra in Dogs: Causes, Symptoms, and Treatment
Dog examined by vet with stethoscope
8 minute read
Heart Murmur in Dogs: Everything You Need to Know
Cat with blue eyes lying on the ground
8 minute read
Pancreatitis in Cats: Causes, Symptoms, & Treatment
Dog in distress with head being held
8 minute read
Addison's Disease in Dogs: Symptoms, Treatment, and Costs
Puppy lying on examination table with IV fluid
6 minute read
Coccidia in Puppies: Symptoms, Diagnosis, Treatment
Cat with ringworm on neck
8 minute read
Ringworm in Cats: Causes, Symptoms & Treatments
Jack Russel with ringworm infection
9 minute read
Ringworm in Dogs: Symptoms, Treatment & Prevention
Dog eating raw meat off cutting board
14 minute read
Can Dogs Eat Raw Meat? Here's Everything You Need to Know
Can reaching onto counter to eat dessert
6 minute read
Can Cats Eat Chocolate?
Dog looking at celery on kitchen counter
9 minute read
Can Dogs Eat Celery? Here's Everything You Need to Know
Dog looking at a carton of eggs
9 minute read
Can Dogs Eat Eggs?
Back to Blog
A family with pets that are insured by Pawlicy Advisor
Pawlicy Advisor is the leading independent marketplace for finding the best coverage for your pet at the lowest rate.
Join 2,438,795+ insured dogs and cats across the US.
Get a Quote
Our pet insurance partners
ASPCA Pet Health Insurance Logo
Pets Best Pet Insurance Logo
Embrace Pet Insurance Logo
Pumpkin Pet Insurance Logo
MetLife Pet Insurance Logo
Prudent Pet Insurance Logo